The Eagles announced the cuts after the new league year began at 4 p.m. ET. Waiting until that point allows the Eagles to designate both players as post-June 1 cuts.
That will free up $4 million in cap space, but the Eagles will still carry more than $9 million in dead money.
Jackson signed with the Eagles in 2019 and missed all but one game of that season with a foot injury. He returned to record 28 tackles and 2.5 sacks last season.
Jeffery dealt with a foot injury the last two seasons and only played in seven games last year. He caught six passes for 115 yards and a touchdown during Philly’s disappointing 2020 campaign.