The 13-time winners hold a slender advantage after winning last month’s first leg 1-0 in Bergamo thanks to a late Ferland Mendy strike.
However, Atalanta have won all of their European away matches this season, including a 2-0 win over Liverpool at Anfield and are aiming to reach the quarter-finals for the second straight season.
Date, time and venue
Real Madrid vs Atalanta is scheduled for an 8pm GMT kick-off on Tuesday, March 16, 2021.
The match will be held behind closed doors at Estadio Alfredo Di Stefano.
How to watch
TV channel: The match will be televised on BT Sport.
Live stream: BT Sport subscribers will be able to watch the match online via the website or BT Sport app.
Eden Hazard has suffered yet another injury setback, with Real Madrid coach Zinedine Zidane has said he is at a loss to explain.
After returning from a muscle problem for the final 15 minutes in Saturday’s last-gasp 2-1 win over Elche, Zidane said Hazard will miss the second leg.
“He won’t be fit. They’re things that I can’t explain. I want to be positive and hope that it’s not too much of a problem,” Zidane said. “Something’s up, because he was never injured in his entire career (before joining Real) or there were very few injuries.
Hazard joins Casemiro on the sidelines, with the Brazilian suspended after picking up a booking in the first leg, however captain Sergio Ramos is fit and likely to start, along with Karim Benzema after an injury-enforced absence.
Atalanta coach Gian Piero Gasperini has almost a full squad available, though defender Remo Freuler is suspended following his red card in the first leg. Madrid will be without the suspended Casemiro because of an accumulation of yellow cards.
Prediction: Real Madrid 2-1 Atalanta
Real Madrid should finish the job on Tuesday, though Atalanta are good enough to make it a nervy evening.
Head to head (h2h) history and results
The only previous meeting between the two teams was the first leg, which Real Madrid won 1-0 in Italy.
Betting odds and tips (subject to change)
- Real Madrid to qualify: 4/11
- Atalanta to qualify: 13/5
- Sergio Ramos to score: 5/1
Additional reporting by Reuters.