He was pronounced dead at the scene, near the busy street’s junction with Grove Road.
A second person, who was found with cuts to their hand, was rushed to hospital for treatment.
There have been no arrests, police said.
A large cordon was in place in Lea Bridge Road, blocking traffic in both directions as forensic officers remained at the scene.
“A man (no further details) was pronounced dead at the scene.
“A second person was found with cuts to their hand and was taken to hospital for treatment.
“Road closures are in place.
“Enquiries are ongoing. At this early stage, there have been no arrests.”